Synthesis of Novel 6,6'-Methylene-bis-[3-(2-anilinoacetyl)-4-hydroxycoumarin] Derivatives

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Synthesis of novel 6,6'-methylene-bis-[3-(2-anilinoacetyl)-4-hydroxycoumarin] derivatives.

The synthesis of novel 6,6'-methylene-bis-[3-(2-anilinoacetyl)-4-hydroxycoumarin] derivatives 6a-f was achieved in excellent yields from 6,6'-methylene-bis-[3-(2-bromoacetyl)-4-hydroxycoumarin] 5 and various arylamines. 5,5'-Methylene-bis-ethylsalicylate 3 was obtained by the esterfication of 5,5'-methylene-bis-salicylic acid 2 with ethanol, which was in turn obtained from salicylic acid 1 and ...

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 2008

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.56.1732